- Best Results8-12 months
- Treatment Recovery6-12 days
- Procedure Time60-120 minutes
- Skin SpecialistDr Davin Lim
- Duration of ResultsLong-term
- Anaesthetic Local
- Back to Work6 days
- Cost$$ Medicare
Vitiligo- Punch grafting
Punch grafting is the oldest method of pigment transfer for vitiligo. It was first used over fifty years ago & has been replaced with ultrathin split thickness grafts & novel melanocyte transfer techniques. Punch grafting remains a useful procedure for undertaking test spots in areas of depigmentation.
FactsFacts on punch grafting for vitiligo
- Punch grafting transfers pigment from one area of skin to another
- Punches are largely outdated as it leaves visible dots & scars
- Single punch grafts are useful to test if vitiligo is stable
- Punch grafting also gives an indication of the speed of re-pigmentation
- Punches are useful to transfer hair follicles to re-pigment white hair
- The smaller the punch, the more natural the outcome
- Despite smaller dermal punches, micrografting gives a superior result
What is punch grafting?
This is the easiest technique to repurpose & transfer pigment cells from one area of skin to another. Punches are cylindrical surgical devices used for biopsies & Follicular unit extraction. It takes less than one second to harvest the donor skin, & a few seconds to transplant it.
What types of punches are used to treat vitiligo?
I use specialized punches that are 1 mm or less. For test spots I use a standard 2-3 mm, depending on the site. Other punches include-
- Keyes punch: an oldie but a goodie. Less tissue trauma.
- FUE punch: many variations of bevels. These are 0.6 to 1.2 mm punches. I use the Cole variety.
- Loo’s punch: thin punch that is bigger than the FUE.
*I do not use punches at present to treat vitiligo. They are useful as test patches to determine stability & rate of pigmentation. Micrografting gives much better results.
Who is a candidate for punch grafting?
Suitable candidates for any vitiligo surgery must have the following criteria-
- Absolute stability of vitiligo for longer than one year.
- Age over 17 years old. Vitiligo in childhood is classified as unstable.
- Absence of trauma associated vitiligo
- Small areas -especially for punch grafting.
- Poliosis or lack of hair pigmentation.
What areas of vitiligo can be treated with punch grafting?
This outdated treatment can be used on areas such as the face, neck, trunk, limbs, including the hands & feet. Super thin punches can be used to treat eyelid & lip vitiligo.
I only use punches in the context of vitiligo as a test patch & or to treat areas of poliosis; absence of pigmentation within hair follicles.
How long does it take to recover from punch grafting?
Recovery depends on the site. Facial areas heal up within 5-7 days. Acral (hands & feet) take 9-14 days. The bigger the punch, the longer it takes for the graft to heal.
Where is the donor site for punch grafting?
Traditionally, the donor sites are the upper thigh or buttock. These areas heal with a stippled hypopigmented pattern (no ideal). For test spots I normally take a small amount of skin from the back of the ear or the front. It heals faster than legs & will not leave a scar.
Are the wounds sutured?
No. For small wounds less than 2 mm, a suture is not required. The recipient site heals up within 5-10 days, whilst the donor site heals up in 7-12 days.
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Are the wounds sutured?
No. For small wounds less than 2 mm, a suture is not required. The recipient site heals up within 5-10 days, whilst the donor site heals up in 7-12 days.
How long does it take before pigmentation is seen?
Pigment is visible immediately after the transplant, however maximal pigmentation takes12 months or longer. Melanocyte migration takes 6 months or longer to move 0.2 to 0.4 mm. The speed of pigmentation depends on the density & size of grafting as well as location, the use of pigment migrators, UVB stimulation & many other factors.
What is the role of punch grafting for vitiligo today?
A punch is sometimes used to test for vitiligo stability & the probability of pigment production. I prefer to punch graft test spots as it only takes 2 seconds to harvest the donor site & about 10 seconds to plant the donor tissue. Most importantly, the donor site heals up within 6 days, compared to spit grafting healing of 2 weeks or more (technically I can do a SSG micrograft free hand).
In summary I perform a test spot if vitiligo is possibly unstable, or if I suspect you have trauma induced (Koebner) vitiligo.
What have I replaced punch grafting with?
I have replaced punch grafting with micrografting as the surgical treatment of choice for vitiligo. Micrografting has the following advantages-
- Quicker results almost 50 times quicker
- More pigmentation in any given area
- More even pigmentation
- Less cobble stoning & scarring
- Faster operation times
Is punch grafting useful to treat white hair in vitiligo patches?
Yes, this is where punch grafts excel. Follicular Unit Extraction is the treatment of choice for patches of poliosis or white hairs. The downside about this procedure is the time taken to remove & replace each strand of hair. Another option is to SSG the whole area & rely on melanocyte migration to re-pigment hair.
I consider factors such as area, site, stability, donor hair density & many other factors before deciding what type of pigment transfer is best for vitiligo patients.
What are other methods to treat vitiligo?
The mainstay of vitiligo treatment is the use of topical anti-inflammatory creams & pigment stimulators. These are prescribed in a pulsed rotation manner. I also use narrowband phototherapy to stimulate melanocytes in patches of vitiligo. Ancillary treatments include vitamins, herbs & diet.
What are other types of surgical treatments?
There are many different surgical treatments including split thickness skin grafts, either whole, meshed, stretched, or hybrid. Melanocytes can also be harvested & cultured in a medium. This takes 3-5 weeks to grow pigment cells, which are then transferred to vitiligo patches.
There are numerous novel transfer kits available to harvest, process then transfer skin cells. These kits are complex & invariably require trypsin enzymes to break down skin before transferring to the recipient site. They include ReCell & Renova. I have been using these kits over the past decade. The success rate is very low. If you really want me to use this because your own research says so, I can do it- at your expense.
Are surgical grafts a cure for vitiligo?
Yes and no. Grafts can cure segmental vitiligo & achromic nevus. They can potentially place stable vitiligo into long term remission. For stable, non-trauma induced vitiligo, surgical grafting can give good long-term results in over 90% of patients.
Where is the donor site taken from?
It depends on the surface area. Test spots are taken from the front or back of the ear. Traditionally, areas of true harvesting include the upper thigh, abdominal area, posterior ear & inner arm.
What are the side effects of punch grafting?
Lots. The main problems with this type of grafting are cobble stoning or raised grafts. Other side effects include scarring at the donor & recipient site, graft failure, as well as irregular pigmentation. The usual side effects of surgery apply to punch grafts, including infections, dyspigmentation, tri-colour changes, etc…
How can unwanted side effects be minimised if your dermatologist uses punch grafts?
Your dermatologist or plastic surgeon has their own way of grafting. Side effects can be minimised by-
- Harvesting thin grafts, namely in a donor site that matches dermal thickness.
- Trimming the fat from the graft
- Using small punches that are less than 1.2 mm wide
- The use of super sharp punches that reduce tissue trauma
- The use of punches smaller than the recipient site defect
- Post op care & appropriate dressings
What are ways to speed up pigmentation?
I use 2 methods to speed up re-pigmentation post-transplant. Firstly, the use of pigment cell migrators, including prostaglandin analogues & calcineurin inhibitors. These are initiated at 14 to 28 days post grafting.
I also use narrowband phototherapy to stimulate the pigment cells within the patches of vitiligo to produce melanin. This procedure is conducted 2-3 times a week & is bulk billed (under Medicare in Australia).
Are there any supplements or dietary changes that can help vitiligo?
Yes. There are papers that encourage dietary changes & supplements. These treatments are banal, with poor evidence. Given the low cost & the fact that placebo can help patients mentally & emotionally, I recommend-
- Vitamins including B12, iron & folate
- Vitamin D supplementation
- Ginkgo biloba herbs
- Diet high in fish oil & antioxidants
- Diet low in acidic foods including citrus fruits & tomatoes
Are children candidates for surgical treatments for vitiligo?
Most children are not surgical candidates, except for segmental (stable) vitiligo, or achromic/nevus depigmentosus. Childhood vitiligo can be progressive. I do not recommend surgical procedures until 17 years of age.
If you have a child with vitiligo, medical treatments including phototherapy & topical creams are first line.
How do you know if you are a candidate for vitiligo surgical grafting?
A thorough history & examination is required prior to surgery. My checklist is as follows-
- Have you tried medical therapy? UVB & topicals?
- Is your vitiligo stable for over a year?
- Is there absence of trauma induced vitiligo?
- Are you older than 17?
- Have you got insight as to the course of vitiligo?
- Are the areas small enough to graft?
What is the cost of vitiligo surgery?
Cost depends on the extent of vitiligo, and the graft technique. As a guide, smaller areas cost $1490 upwards. This includes theatre costs, nursing & post-operative care.
Any phototherapy sessions are bulk billed if you have Medicare. This saves approximately $7500 per annum.
Davin’s Viewpoint on punch grafting for vitiligo
Grafting is one of the oldest surgical procedures for vitiligo, made famous by the brilliant dermatologist Dr Norman Orentreich from New York. Incidentally this dermatologist also invented surgical subcision, as well as hair transplantation & cosmetic injectables. Pure genius.
Fast forward to 2022 & beyond, punch grafting & suction blister grafts are now no longer practices, replaced by technology such as micrografting, ReCell & Renova tissue grafts. I occasionally use punches as test spots only, as they are more convenient for the patient (as compared to the donor harvest of SSG). A well-positioned punch allows me to ascertain take up of the graft & rate of pigment transfer. This is especially useful if one is unsure if vitiligo is progressive & or subject to Koebner. I normally review the graft at 6 to 8 months. Patients are not encouraged to see me before that, as pigment migration is much, much slower than watching grass grow.
Why a test spot in some cases? Because the surgical process of micrografting takes a significant number of resources including time for both patients & my clinical team. Recovery following grafting can take a few weeks. A test spot is not absolute, but in cases that are not clear (stability not diagnosis), it can be useful.
Punches invariably give a cobblestone appearance, hence why they are now replaced with newer techniques of repurposing melanocytes. I can correct old punch grafts, with resurfacing & re-grafting, if this applies to you.