Unlike volume enhancing dermal fillers which are placed deep, Hybrid dermal fillers are placed within the dermis. This allows for perfect tissue integration. These procollagen molecules will start to work immediately after injection with maximal results 6 to12 weeks later.

Results can be seen as early as one week after the first injection, however maximal results are seen after 6 weeks from the second injection. Collagen production takes time. Unlike fillers that provide volume, this filler activates your immune system to produce collagen & hyaluronic acid. Its unique structure allows it to flow freely through the subcutaneous tissue and dermis in the target areas.

2, spaced one month apart. For extreme sun damage & laxity, another session at week 12 can further improve skin quality & wrinkles. The same applies to the decollete, hands & neck areas.

This new hybrid dermal filler lasts 6 – 8 months if 2 treatments are given one month apart. After the initial treatments, we recommend retreatment once to twice a year. 

Older fillers such as poly-L-lactic acid & calcium hydroxyapatite last longer, however they do not produce as much collagen as compared with Hybrid fillers. 

The Bio Aesthetic Points technique addresses the 5 key areas of the face to provide maximal collagen stimulation, in turn reducing wrinkles, sun damage, crepey & lax skin​. These key areas are slightly modified taking into account facial shape. 

When performed with skill & precision the result will look natural. Hybrid fillers address facial aging including skin laxity & quality, with minimal volume changes. Traditional hyaluronic acid dermal fillers improve skin.

Yes, however there is a ‘cooling off’ period of up to three months. Hybrid fillers stimulate collagen production, whilst traditional fillers provide volume. In most cases traditional fillers lie a deeper plane.

Fillers for the under eyes is one of our most requested places to rejuvenate, however it is also the most complex. Under eye area is off label however our senior dermatologists can assess this area to see if this filler is right for your goals.

12 to 24 hours. Yes, it’s that quick. The time-line goes something like this-

• First 2-4 hours; filler integrates into the surrounding tissue.
• Next 4-12 hours; full integration.
• Results; in a few days to weeks.
• Repeat injection; 28 days later. 
• Maximal results; at 3 months+

With marked UV exposure the skin on the face, neck & decolletage becomes dull, pigmented & wrinkly. There are few places in the World that get the same amount of UV as Brisbane. In my experience, patients with significant sun damage will benefit from a third dose of Hybrid filler, 28 days after the second.

NAHYCO® technology Hybrid fillers provide great tissue integration- think of honey on a piece of toast. It is not designed to replace volume. It does not aid in projection & structure as compared to traditional fillers. For this job a thicker cross-linked gel is required.

For cheekbone contouring, temple fillers, jawline & chin, you will require a firm hyaluronic acid filler. 

Traditional collagen stimulating fillers include calcium hydroxyapatite & poly-L-lactic acid. These fillers are excellent for improving skin texture however there are a few disadvantages-

• CaOh & PLLA fillers are off-label hyperdiluted. This means we require titration of the concentration for each patient. 

• Tissue intertration is better with Hybrid fillers.

• Hybrid dermal fillers can be reversed with an enzyme called hyaluronidase. 

• Results can be delayed for up to 3-6 months, as compared to an earlier result with Hybrid fillers. 

In many cases, yes. It can be used to reduce fine lines & wrinkles, however if  there is dynamic movement, anti-wrinkle injections may be required. For super deep wrinkles, lasers or deep peeling solutions may be required. 

Dermal fillers can be combined with the following methods to improve skin quality.

Fractional lasers: include 1927, Hybrid & CO2 resurfacing. These types of lasers can be performed one week before or after Hybrid fillers (7 day guide is the minimum time between sessions).

IPL & BBL: can be employed the same day as filling. This is because IPL is delivered superficially. IPL  improves  pigmentation such as redness & discolouration.

Pico Lasers such as Picoway & Picosure Pro can be performed on the same day as Hybrid fillers. Pico lasers have little or no downtime.

Skin care: antioxidants, retinol & skin acids. Skin care is best as a preventative step.

Chemical peels: include AHA & retinoic acid peels. Jessner TCA peels are awesome at addressing deep issues such as wrinkles, pigmentation & sun damage.

Threads & devices: PDO & cog threads can improve skin laxity. These are best combined with energy devices such as Ultherapy & radiofrequency.

Although numbing cream can be used, most patients do not require it as injections are well tolerated. The structure of Hybrid fillers are different from anti-wrinkle creams, meaning that it does not sting. The whole session is completed in 1-2 minutes.

Treatments by our experienced nurse injectors are $1600 for 2 treatments.

Treatments by our senior procedural dermatologists are $1800 for 2 sessions.

Laser & filler packages start from $1790. 

Decollete & neck 3 sessions; discounted by your injector.

Here is a quick guide to understand the differences between anti wrinkle injections & Hybrid fillers;

• Anti-wrinkle injections are great for wrinkles caused by movement; examples include the crow’s feet, frown & forehead wrinkles.
• Volumising dermal fillers provide volume & soft tissue support.
• Hybrid dermal fillers provide collagen stimulation with little or no volume changes.

  

This filler has a long safety record. Injection related side effects are localized & short lived. 

• Swelling, redness, slight bruising.
• Occasionally itching, pain/tenderness. It is self limiting.
• Rare risks such as blindness, loss of blood supply to an area of skin and infection associated with the filler product have been reported in literature. These are treatable if managed appropriately.
• Filler nodules or lumps, & infection. As Hybrid dermal fillers integrate well with surrounding tissue, persistent lumps are very rare.

There are many other options to improve skin quality as discussed above. The advantage of Hybrid fillers is that they do not have any downtime, as compared to lasers, radiofrequency & HIFU.

In the context of dermal hydration, HA fillers provide a more consistent outcome, as compared to energy devices. An important concept to understand is as follows-

• Lasers, microneedling, peels, radiofrequency & focused ultrasound all rely on your body’s immune system to kick in & lay down collagen. Some people do this well, hence the lie on the right side of the bell curve (for collagen stimulation).

• Hybrid fillers rely less on collagen remodeling as it provides instant hydration & delayed collagen remodeling. Thus, if your immune system can’t produce collagen, you still have the hyaluronic acid component to rehydrate your skin. 

With expert delivery, Profhilo will not make your face look puffy or fat. That’s because Profhilo does not create volume. It works by hydrating & strengthening the skin from within. This filler is excellent for patients with good facial volume, with mild to moderate wrinkling.

Yes. The body can be treated safely (on label use). Commonly treated areas include the underarms, knees & abdomen. Between 2-3 sessions are required, spaced 28 days apart. 

Though marketed as a skin tightening & lifting dermal filler, the true value of Profhilo is to reduce fine wrinkles through collagen production. The actual lifting properties of Hybrid lasers are limited.

Profhilo can be used on the same day as IPL or pico lasers. We don’t routinely perform deeper fractional lasers concurrently with Profhilo. Lasers do not break down dermal filler as fillers are stable up to >100 degrees for several minutes. 

Profhilo has been shown to improve atrophic acne scars. A recent paper has shown its efficacy in a study group of over 60 patients, with a control arm (saline). This publication  is the largest & most robust research paper studying the effects of dermal fillers & volume correction. 

Unlike other HA fillers that only provide volume, the consistency of Profhilo enables it to integrate in tissue that has not been extensively subcised. The regenerative capacity of hybrid fillers may be as good as other collagen stimulating fillers, with better tissue match & the option to reverse it, should it be required. Future studies will reveal.

Profhilo hydrates the deep dermal layer of skin, giving it a youthful glow. It also reduces skin laxity, improves wrinkles & other signs of aging.

Skin aging is more complex than just filling. It encompases skin care, diet, lifestyle, genetics, & other treatment modalities to help stimulate collagen, elastin & ground substance. 

Profhilo has been widely used in Europe for the past five years & in New Zealand for over 2 years. To date, well over a million syringes have been injected. This filler has a robust well-established safety profile.

Profhilo is contraindicated in those who are allergic to hyaluronan; pregnant or breast-feeding. It is best avoided if you have had a recent vaccination or a cold (2 weeks or less). Caution is needed in those with autoimmune disorders.